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Jan 02, 2025
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CHEM 6140 - Introduction to Mass Spectrometry
Graduate course covering fundamental aspects and applications of Mass Spectrometry (MS). Quasi-equilibrium theory, isotope effects, and gas phase chemistry will serve to describe ion formation, excitation, and fragmentation. Methods of ionization (electron impact, electrospray, matrix-assisted laser desorption ionization) and instrumentation (quadrupole, ion trap, time-of-flight, ion cyclotron resonance) will be introduced. Practical aspects regarding application of MS (sample preparation, gas chromatography, liquid chromatography) to biological mixtures and data analysis will also be discussed.
When Offered: Spring term annually.
Credit Hours: 2
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