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Rensselaer Catalog 2014-2015 [Archived Catalog]
Courses
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ARTS 6940 - Studies in Electronic Arts
Individual and collaborative projects and readings adapted to the needs of individual students at the advanced level.
When Offered: Fall and spring terms annually.
Credit Hours: 4 to 6
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ARTS 6960 - Topics in Electronic Arts
Credit Hours: 3 to 6
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ARTS 6990 - Master’s Thesis
Active participation in research, under the supervision of a faculty adviser, leading to a master’s thesis. Grades of S or U are assigned by the adviser each term to reflect the student’s research progress for the given semester. Once the thesis has been presented, approved by the adviser, and accepted by the Office of Graduate Education, it will be archived in a standard format in the library.
Credit Hours: 1 to 9
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ARTS 9990 - Dissertation
Active participation in research, under the supervision of a faculty adviser, leading to a doctoral dissertation. Grades of IP are assigned until the dissertation has been publicly defended, approved by the doctoral committee, and accepted by the Office of Graduate Education to be archived in a standard format in the library. Grades will then be listed as S.
When Offered: Fall and spring terms annually.
Credit Hours: Variable credit, up to 12 hours per semester.
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ASTR 1510 - Quasars and Cosmology
An introduction to the origin and large-scale structure of the Universe. Topics to be covered include: the contents and geometry of the Universe, the Big Bang model, particle physics and the formation of the elements, galaxy formation, dark matter, black holes, and active galactic nuclei. If ASTR 1510 is taken as a one-credit course, it will be graded satisfactory/unsatisfactory and it cannot be counted towards the Institute’s baccalaureate requirement of 24 credits in the sciences. If ASTR 1510 is taken as a two-credit course, it will be graded in the conventional manner. If ASTR 1510 and ASTR 1530 are both taken as graded two-credit courses, they may be counted together as one four-credit elective for nonscience majors.
When Offered: Fall term annually.
Credit Hours: 1 or 2
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ASTR 1530 - Tour of the Solar System
A survey of the solar system based on recent results from ground-based observations and space probes. Topics to be covered include: the sun, moon, Venus, Mars, the giant planets, comets, and the search for life in the solar system. If ASTR 1530 is taken as a one-credit course, it will be graded satisfactory/unsatisfactory, and it cannot be counted towards the Institute’s baccalaureate requirement of 24 credits in the sciences. If ASTR 1530 is taken as a two-credit course, it will be graded in the conventional manner. If ASTR 1510 and ASTR 1530 are both taken as graded two-credit courses, they may be counted together as one four-credit elective for nonscience majors.
When Offered: Spring term annually.
Credit Hours: 1 or 2
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ASTR 1960 - Topics in Astronomy and Astrophysics
Credit Hours: 1
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ASTR 2050 - Introductory Astronomy and Astrophysics
Astronomy for students with a background of college mathematics and physics. Topics include: astrophysical concepts, solar system basics, stellar astronomy and the interstellar medium, the Milky Way system, galaxies, quasars, and cosmology.
Prerequisites/Corequisites: Corequisite: PHYS 1200.
When Offered: Spring term annually.
Credit Hours: 4
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ASTR 2120 - Earth and Sky
An introduction to astronomy from an observational perspective. Students will learn the basics of observing the night-time sky, both with the unaided eye and through telescopic observation. Observations of Earth from orbiting satellites will also be discussed. The course is suitable for nonphysics and nonscience majors as well as those committed to specialization in Astronomy. Includes evening laboratory sessions.
When Offered: Fall term annually.
Credit Hours: 4
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ASTR 2940 - Special Projects in Astronomy
Study and research in various fields of astronomy to demonstrate interest in and ability for independent work.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Fall and spring terms annually.
Credit Hours: 3
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ASTR 4120 - Observational Astronomy
An introduction to astronomical observing techniques and instrumentation. Optical telescope design. Observatory site selection. Telescopes above the atmosphere. Imaging techniques: photography, charge-coupled devices. Optical photometry, spectroscopy, and polarimetry, and their applications. Infrared techniques and applications. Radio astronomy. Includes evening laboratory sessions.
Prerequisites/Corequisites: Prerequisite: ASTR 2050 or permission of instructor.
When Offered: Fall term annually.
Credit Hours: 4
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ASTR 4220 - Astrophysics
A survey course in modern astrophysics with an emphasis on stellar astrophysics and interstellar matter; topics include star formation, the structure and observable properties of normal and degenerate stars; and the composition, dynamics, and stability of the interstellar medium.
Prerequisites/Corequisites: PHYS 2220 and PHYS 4420 or equivalent.
When Offered: Fall term annually.
Credit Hours: 4
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ASTR 4240 - Gravitation and Cosmology
Introduction to the physics of gravitation and spacetime. Special relativity, tensor calculus, and relativistic electrodynamics. General relativity with selected applications of Einstein’s field equations (gravitational time dilation; gravitational lensing; frame dragging; gravitational radiation). The physics of nonrotating and rotating black holes. Relativistic models for the large-scale structure of the Universe. Observational constraints on the cosmological parameters. Big Bang nucleosynthesis, the Cosmic Background Radiation. A culminating experience project is required. (Meets with PHYS 4240.)
Prerequisites/Corequisites: Prerequisite: PHYS 4330 and MATH 4600.
When Offered: Spring term annually.
Cross Listed: Cross listed with PHYS 4240. Students cannot receive credit for both ASTR 4240 and PHYS 4240.
Credit Hours: 4
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ASTR 4510 - Origin of Life: A Cosmic Perspective
To understand the origin of life is a fundamental goal of science. Discussions include evidence for important prebiotic molecules in the clouds from which new planetary systems are born, and compare cosmic and terrestrial sources of such molecules on the primitive Earth. The course is multidisciplinary, covering topics in physics, astronomy, chemistry, earth sciences, and biology.
Prerequisites/Corequisites: Prerequisite: ASTR 2050 or permission of instructor.
When Offered: Spring term annually.
Credit Hours: 3
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ASTR 4900 - Astrophysics Undergraduate Seminar
Discussion of topics in the current astrophysical literature. Each student is required to give one oral presentation based on a paper or group of papers.
Prerequisites/Corequisites: Prerequisite: junior standing or higher, or permission of instructor.
When Offered: Fall and spring terms annually.
Credit Hours: 1
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ASTR 4940 - Special Projects in Astronomy
Study and research in various fields of astronomy to demonstrate interest in and ability for independent work.
Prerequisites/Corequisites: Prerequisite: permission of instructor.
When Offered: Fall and spring terms annually.
Credit Hours: 3
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ASTR 4960 - Topics in Astronomy and Astrophysics
Credit Hours: 4
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ASTR 6250 - Interstellar Medium
Thermal structure and dynamics of the interstellar medium. Topics include diffuse nebulae, composition of interstellar dust and relation to extinction and polarization, molecules and interstellar chemistry, physics of star-forming regions.
Prerequisites/Corequisites: Prerequisite: ASTR 4220.
When Offered: Consult department about when offered.
Credit Hours: 3
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ASTR 6900 - Astrophysics Seminar
Discussion of topics in the current astrophysical literature. Each student is required to give an oral presentation based on a paper or group of papers. For graduate students only.
When Offered: Fall and spring terms annually.
Credit Hours: 1
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ASTR 6940 - Readings in Astronomy and Astrophysics
Credit Hours: 3
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ASTR 6960 - Special Topics in Astronomy and Astrophysics
Supervised reading and study in various fields of astrophysics.
Credit Hours: 3
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ASTR 6970 - Professional Project
Active participation in a semester-long project, under the supervision of a faculty adviser. A Professional Project often serves as a culminating experience for a Professional Master’s program but, with departmental or school approval, can be used to fulfill other program requirements. With approval, students may register for more than one Professional Project. Professional Projects must result in documentation established by each department or school, but are not submitted to the Office of Graduate Education and are not archived in the library. Grades of A, B, C, or F are assigned by the faculty adviser at the end of the semester. If not completed on time, a formal Incomplete grade may be assigned by the faculty adviser, listing the work remaining to be completed and the time limit for completing this work.
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BCBP 2900 - Research in Biochemistry/Biophysics
Hands-on research in a faculty member’s research laboratory.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Fall and spring terms annually.
Credit Hours: 3 to 4
Contact, Lecture or Lab Hours: 9 to 12 contact hours
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BCBP 2930 - Out-of-Classroom Experience in Biochemistry/Biophysics
Credit to be given for an out-of-classroom experience related to biochemistry and/or biophysics (BCBP) having intellectual content relevant to the student’s educational or career goals, subject to approval of a written proposal and a final written report. The adviser (for BCBP majors) or, with permission, any BCBP faculty member may serve as evaluator. For each out-of-classroom experience a student may register only once.
Credit Hours: 1 to 4
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BCBP 2940 - Readings in Biochemistry/Biophysics
Independent study of selected readings in the fields of biochemistry and biophysics, supervised by a faculty member.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Fall and spring terms annually.
Credit Hours: 1 to 4
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BCBP 4310 - Genetic Engineering
In this course, students will explore the molecular methods and applications of recombinant DNA technology and the issues regarding their use through case studies on the effect of genetic engineering in medicine, agriculture, biology, forensics, and various other areas of technology. The course has three major components: 1) techniques used in the generation of recombinant molecules, 2) application of recombinant technology to diagnostics and therapeutics and 3) genetically modified organisms. May be used to fulfill the Culminating Experience requirement in Biology. (Students cannot obtain credit for both this course and BCBP 6310.)
Prerequisites/Corequisites: Prerequisites or corequisites: BCBP 4760 and BIOL 4620, or permission of instructor.
When Offered: Spring term annually.
Credit Hours: 4
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BCBP 4550 - Molecular Modeling
This course covers the theory and practice of the structural modeling of proteins and other biomolecules using informatics-driven and energy-based approaches. Topics include template-based comparative modeling, secondary structure prediction, tertiary structure prediction, protein classification, sidechain rotamers, docking, protein design, energy minimization, electrostatics, molecular dynamics, and molecular surfaces. Molecular modeling software will be provided. Laptop computers are required. BIOL 4550, BIOL 6420, BCBP 4550, and BCBP 6420 meet jointly; only one of these courses can be taken for credit.
Prerequisites/Corequisites: Prerequisite: MATH 1020, BIOL 4620, BIOL 4760.
When Offered: Spring term annually.
Cross Listed: BIOL 4550/6420, BCBP 4550/6420.
Credit Hours: 4
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BCBP 4640 - Proteomics
Characterization of patterns and changes in patterns of protein expression with development, aging, and disease. Protein separation and quantification strategies; mass spectrometry and analysis of spectra; protein profiling, biomarkers, post-translational modifications; current applications; emerging technologies and applications. Individual presentations on relevant topics will be expected. (Students cannot obtain credit for this course and BIOL 4640, BCBP 6640 or BIOL 6640.)
Prerequisites/Corequisites: Prerequisite: BCBP 4760 or equivalent.
When Offered: Spring term annually.
Credit Hours: 4
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BCBP 4710 - Biochemistry Laboratory
Major principles of biochemistry are illustrated as students purify and analyze specific proteins. Experience is obtained with various techniques including protein extraction from bacteria and tissues, chromatography, ultracentrifugation, spectrophotometric analysis, and electrophoresis. The course includes extensive hands-on laboratory work, as well as the writing of in-depth reports. (Students cannot obtain credit for both this course and BIOL 4710.) This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: BIOL 1010, BIOL 2120.
When Offered: Spring term annually.
Credit Hours: 4
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BCBP 4760 - Molecular Biochemistry I
Part I of a two-semester sequence focusing on the chemistry, structure, and function of biological molecules, macromolecules, and systems. Topics covered include protein and nucleic acid structure, enzymology, mechanisms of catalysis, regulation, lipids and membranes, carbohydrates, bioenergetics, and carbohydrate metabolism. (Students cannot obtain credit for both this course and either BIOL 4760 or CHEM 4760.)
Prerequisites/Corequisites: Prerequisites or corequisites: CHEM 2250 and BIOL 1010 or BIOL 2120 or equivalents.
When Offered: Fall term annually.
Cross Listed: Cross listed as BIOL 4760 and CHEM 4760.
Credit Hours: 4
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BCBP 4770 - Molecular Biochemistry II
The second semester of the molecular biochemistry sequence. Topics include lipids and lipid metabolism, amino acid metabolism and the coenzymes involved in this metabolism, nucleic acid synthesis and chemistry, protein synthesis and degradation, integration of metabolism, photobiology, and photosynthesis. This course is taught in studio mode. (Students cannot obtain credit for both this course and either BIOL 4770 or CHEM 4770.)
Prerequisites/Corequisites: Prerequisite: BCBP 4760 or equivalent.
When Offered: Spring term annually.
Cross Listed: Cross listed as BIOL 4770 and CHEM 4770.
Credit Hours: 4
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BCBP 4780 - Protein Folding
The biophysical mechanism of protein folding and the role of misfolding in human diseases is explored. The course will introduce principles of protein structure, protein folding in the cell, and thermodynamic and kinetic methods for studying protein folding in vitro. The course will also involve a literature-based discussion of human diseases related to protein folding defects, including Alzheimer’s and other amyloid diseases, cystic fibrosis, and Prion-related syndromes.
Prerequisites/Corequisites: Prerequisite: BCBP 4760 or equivalent. (Students may not receive credit for both this course and BCBP 6780, CHEM 4780, or CHEM 6780.)
When Offered: Spring term even-numbered years.
Credit Hours: 4
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BCBP 4800 - Methods in Biophysics
Biophysics addresses the physical principles of biological function, which requires the application of physical methods. The focus of this course is on methods used to study the interactions and dynamics of biomolecules in vitro, primarily proteins and nucleic acids. We will cover both the theoretical and methodological aspects of molecular biophysical methods. Thios course is designed as an interdisciplinary introduction to the field and is open to students in Biology, Chemistry, Physics, or Engineering.
Prerequisites/Corequisites: Presrequisite: BCBP 4760 or permission of instructor.
When Offered: Fall term annually.
Cross Listed: With BCBP 6800. Students cannot receive credit for both BCBP 4800 and BCBP 6800.
Credit Hours: 4
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BCBP 4870 - Protein Structure Determination
X-ray crystallography and nuclear magnetic resonance (NMR) are used to determine 3-D structures of biological macromolecules at atomic resolution. The course will cover crystallographic and NMR methods, their theory and practice, along with thermodynamics of structure formation and molecular dynamics. Students will prepare a poster presentation on a protein of their choice. (Students cannot obtain credit for both this course and BCBP 6870.)
Prerequisites/Corequisites: Prerequisites: BCBP 4760, MATH 1020, and PHYS 1200 or equivalents.
When Offered: Fall term even-numbered years.
Credit Hours: 4
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BCBP 4990 - Senior Research Thesis
Independent laboratory research, on or off campus, supervised by a faculty member, culminating in a written thesis; or literature research culminating in the writing of a review article. The thesis research must also be presented in the form of a poster presentation or a talk. This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: permission of instructor.
When Offered: Fall and spring terms annually.
Credit Hours: 4
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BCBP 6170 - Advanced Topics in Nuclear Magnetic Resonance
Advanced graduate course covering fundamental aspects of NMR common for application in a broad range of fields. Classical and quantum-mechanical descriptions are utilized to explore information content of NMR pulse sequences. The latter approach includes density matrix theory and proceeds with the product-operator formalism. Practical aspects and data analysis are also described. Subsequent focus is on liquid-state NMR of biological macromolecules, including resonance assignment and determination of molecular structure and dynamics. (Students cannot obtain credit for both this course and CHEM 6170.)
Prerequisites/Corequisites: Prerequisite: CHEM 4410 or equivalent.
When Offered: Spring term annually.
Credit Hours: 4
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BCBP 6310 - Genetic Engineering
In this course, students will explore the molecular methods and applications of recombinant DNA technology and the issues regarding their use through case studies on the effect of genetic engineering on medicine, agriculture, biology, forensics, and various other areas of technology. The course has three major components: 1) techniques used in the generation of recombinant molecules, 2) application of recombinant technology to diagnostics and therapeutics and 3) genetically modified organisms. May be used to fulfill the Culminating Experience requirement in Biology.
Prerequisites/Corequisites: Undergraduate course in molecular biology and biochemistry or permission of instructor. (Students cannot obtain credit for both this course and BCBP 4310.)
When Offered: Spring term annually.
Credit Hours: 4
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BCBP 6420 - Molecular Modeling
This course covers the theory and practice of the structural modeling of proteins and other biomolecules using informatics-driven and energy-based approaches. Topics include template-based comparative modeling, secondary structure prediction, tertiary structure prediction, protein classification, sidechain rotamers, docking, protein design, energy minimization, electrostatics, molecular dynamics, and molecular surfaces. Molecular modeling software will be provided. Laptop computers are required. BIOL 4550, BIOL 6420, BCBP 4550, and BCBP 6420 meet jointly; only one of these courses can be taken for credit.
Prerequisites/Corequisites: Prerequisite: MATH 1020, BIOL 4620, BIOL 4760.
When Offered: Spring term annually.
Cross Listed: BIOL 4550/6420, BCBP 4550/6420.
Credit Hours: 4
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BCBP 6550 - Ethical Issues in Biotechnology
This course reviews the principles of ethical behavior and responsible conduct of research and discusses specific areas of biotechnology research, medical research and societal issues in the context of these principles. Representative topics include genetic engineering, stem cell research, assisted reproduction, human subjects, animal research and nanotechnology. Active student participation is expected.
Prerequisites/Corequisites: Undergraduate registration only with permission of instructor.
When Offered: Fall term annually.
Cross Listed: BMED 6700 and BIOL 6550. Students may not receive credit for both BCBP 6550 BIOL 6550 or BMED 6700.
Credit Hours: 3
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BCBP 6640 - Proteomics
Characterization of patterns and changes in patterns of protein expression with development, aging, and disease. Protein separation and quantification strategies; mass spectrometry and analysis of spectra; protein profiling, biomarkers, post-translational modifications; current applications; emerging technologies and applications. Individual presentations on relevant topics will be expected. (Students cannot obtain credit for this course and BCBP 4640, BIOL 4640, or BIOL 6640.)
Prerequisites/Corequisites: Prerequisite: BCBP 4760 or equivalent.
When Offered: Spring term annually.
Credit Hours: 3
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BCBP 6780 - Protein Folding
The biophysical mechanism of protein folding and the role of misfolding in human diseases is explored. The course will introduce principles of protein structure, protein folding in the cell, and thermodynamic and kinetic methods for studying protein folding in vitro. The course will also involve a literature-based discussion of human diseases related to protein folding defects, including Alzheimer’s and other amyloid diseases, cystic fibrosis, and Prion-related syndromes. (Students may not receive credit for both this course and BCBP 4780, CHEM 4780, or CHEM 6780.)
Prerequisites/Corequisites: Prerequisite: BCBP 4760 or equivalent.
When Offered: Spring term even-numbered years.
Credit Hours: 4
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BCBP 6800 - Methods in Biophysics
Biophysics addresses the physical principles of biological function, which requires the application of physical methods. The focus of this course is on methods used to study the interactions and dynamics of biomolecules in vitro, primarily proteins and nucleic acids. We will cover both the theoretical and methodological aspects of molecular biophysical methods. Thios course is designed as an interdisciplinary introduction to the field and is open to students in Biology, Chemistry, Physics, or Engineering.
Prerequisites/Corequisites: Prerequisite: BCBP 4760 or permission of instructor.
When Offered: Fall semester annually.
Cross Listed: With BCBP 4800. Students cannot receive credit for both BCBP 4800 and BCBP 6800.
Credit Hours: 4
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BCBP 6870 - Protein Structure Determination
X-ray crystallography and nuclear magnetic resonance (NMR) are used to determine 3-D structures of biological macromolecules at atomic resolution. The course will cover crystallographic and NMR methods, their theory and practice, along with thermodynamics of structure formation and molecular dynamics. Students will prepare an oral presentation on a protein of their choice. (Students cannot obtain credit for both this course and BCBP 4870.)
Prerequisites/Corequisites: Prerequisites: BCBP 4760, MATH 1020, and PHYS 1200 or equivalents.
When Offered: Fall term even-numbered years.
Credit Hours: 4
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BCBP 6910 - Research Rotation
The student will perform hands on research in the lab of a BCBP faculty to learn basic research methods and techniques, accomplish a small research project and determine whether the lab is a good fit for thesis research.
Prerequisites/Corequisites: Restricted to first year BCBP graduate students.
When Offered: Spring and fall terms annually.
Credit Hours: 2-4
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BCBP 6940 - Readings in Biochemistry/Biophysics
Independent study of selected readings in the fields of biochemistry and biophysics, supervised by a faculty member.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Fall and spring terms annually.
Credit Hours: 1 to 4
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BCBP 6970 - Professional Project
Active participation in a semester-long project, under the supervision of a faculty adviser. A Professional Project often serves as a culminating experience for a Professional Master’s program but, with departmental or school approval, can be used to fulfill other program requirements. With approval, students may register for more than one Professional Project. Professional Projects must result in documentation established by each department or school, but are not submitted to the Office of Graduate Education and are not archived in the library. Grades of A, B, C, or F are assigned by the faculty adviser at the end of the semester. If not completed on time, a formal Incomplete grade may be assigned by the faculty adviser, listing the work remaining to be completed and the time limit for completing this work.
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BCBP 6990 - Master’s Thesis
Active participation in research, under the supervision of a faculty adviser, leading to a master’s thesis. Grades of S or U are assigned by the adviser each term to reflect the student’s research progress for the given semester. Once the thesis has been presentend, approved by the adviser, and accepted by the Office of Graduate Education, it will be archived in a standard format in the library.
Credit Hours: 1 to 9
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BCBP 9990 - Dissertation
Active participation in research, under the supervision of a faculty adviser, leading to a doctoral dissertation. Grades of IP are assigned until the dissertation has been publicly defended, approved by the doctoral committee, and accepted by the Office of Graduate Education to be archived in a standard format in the library. Grades will then be listed as S.
Credit Hours: Variable
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BIOL 1010 - Introduction to Biology
Introduction to biological systems. Discussion of problems associated with biological organization, scaling, and hierarchy. Major topics covered include evolution, genetics, molecular biology and biotechnology, and ecology. The course considers the biological components of various societal and individual problems. Taught in Web-based, interactive studio mode with emphasis on biological simulations, problem solving, and peer teaching methods.
Prerequisites/Corequisites: BIOL 1015 - Introduction to Biology Laboratory is a corequisite.
When Offered: Fall and spring terms annually.
Credit Hours: 3
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BIOL 1015 - Introduction to Biology Laboratory
The goal of this laboratory course is to learn about biology through hands-on, project-based lab activities that engage students in actual biology experiments and procedures - learning biology by actually doing biology.
Prerequisites/Corequisites: Corequisite: BIOL 1010 Introduction to Biology.
When Offered: Fall and spring terms annually.
Credit Hours: 1
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BIOL 2120 - Introduction to Cell and Molecular Biology
Structural and functional relationships of cells are discussed with regard to similarities among all living organisms. Introduction to cellular biochemistry, metabolism and energy flow, cellular and Mendelian genetics, and the chemical basis of heredity. The laboratory exercises illustrate current concepts in cellular and molecular biology.
When Offered: Spring term annually.
Credit Hours: 4
Contact, Lecture or Lab Hours: 6 contact hours
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BIOL 2500 - Genetics and Evolution
Mechanisms of inheritance in eukaryotes and prokaryotes; genetic mapping, gene expression, cloning and sequencing; quantitative and population genetics, and synthetic theory of evolution.
Prerequisites/Corequisites: Prerequisite: BIOL 2120.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 2900 - Research in Biology
Independent study program for the purpose of developing research skills under the guidance of a faculty member. This course may be repeated and it cannot count as a biology elective.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Fall, spring, and summer terms annually.
Credit Hours: 1 to 4
Contact, Lecture or Lab Hours: 3 to 12 contact hours
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BIOL 2930 - Out-of-Classroom Experience in Biology
Credit to be given for an out-of-classroom experience related to biology having intellectual content relevant to the student’s educational or career goals, subject to approval of a written proposal and a final report. The adviser (for biology majors) or, with permission, any Biology faculty member may serve as evaluator. For each out-of-classroom experience, a student may register only once for one to four credit hours. This course cannot be used as a biology elective.
Prerequisites/Corequisites: Permission of instructor
When Offered: Fall, spring, and summer terms annually.
Credit Hours: 1 to 4
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BIOL 4020 - Stem Cell Laboratory
This laboratory course will use cell culture and various biochemical techniques to study cultured human stem cells. After learning basic cell culture methods, a class project will be assigned for the class to complete, and each student will be responsible for designing and completing the lab work for a single component of the overall project. May be used to fulfill the Culminating Experience requirement in Biology.
Prerequisites/Corequisites: Completion of Advanced Laboratory Requirement for Biology.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 4050 - Literature Search Strategies in Biology
Course covers basic library offerings such as ConnectNY, My RensSearch, and Interlibrary Loan and complex ones such as Sci-Finder Scholar, Web of Science and Medline. Different types of information retrieval including ebooks, journal articles, protocols, patents, and grants are included. Students visit archives, and guest librarians are invited to lecture on their areas of expertise.
When Offered: Fall term annually.
Credit Hours: 1
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BIOL 4060 - Cancer Cell Research
Each student is assigned a specific research problem within the general area of cancer cell interactions with the normal tissue microenvironment. Students will use a wide range of techniques, including cell culture, immunofluorescence microscopy, and Western blotting. This laboratory course can serve as a culminating experience for seniors who have previously been involved in independent research involving in vitro cancer cells. This course can be used to fulfill the Culminating Experience in Biology. This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: BIOL 4260 or BIOL 4740 and permission of instructor.
When Offered: Fall and spring terms annually.
Credit Hours: 4
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BIOL 4090 - Seminal Developments in Biomedical Research
Recent developments in biomedical research will be discussed in a moderator-led classroom discussion. Topics may vary by semester but will all relate scientific discoveries to clinical applications and research. Students will make presentations during the semester. Open to students in the accelerated physician-scientist program only.
When Offered: Spring term annually.
Credit Hours: 2
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BIOL 4100 - From Neuron to Behavior
A detailed survey of important topics in the neurosciences. Some of the topics to be covered in this class are: basic mechanisms of neural signaling (neurophysiology, synaptic transmission, and molecular signaling); understanding of sensation/movement and in particular how it relates to neuroanatomy; neurodevelopment and how the mature brain can change (plasticity), and; complex brainfunctions and neurological disease. Taught together with BIOL 6100. Although there is extra work associated with the 6100 course, both courses may not be taken for credit.
Prerequisites/Corequisites: BIOL 1010, BIOL 2120 or permission of the instructor.
When Offered: Spring term annually.
Cross Listed: BIOL 6100
Credit Hours: 4
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BIOL 4200 - Biostatistics
An introduction to the concepts and techniques of modern statistics. Computer-based, in-class sessions will emphasize hands-on application of statistical techniques using data and examples drawn from the biological and medical sciences. Pre-class, online exercises will prepare students for in-depth classroom explorations. Topics covered will include sampling, regression, analysis of variance, and factor analysis, MANOVA, maximum liklihood methods, discriminant analysis, time series analysis, and forecasting. The final project requires analysis of a major research-related data set and write-up of results in the format of a scientific paper.
Prerequisites/Corequisites: BIOL 1010, MATH 1010, or permission of the instructor.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 4250 - Developmental Biology
Model systems provide the experimental basis for understanding the conserved principles of developmental biology. This class will cover fundamental topics including axis specification, pattern formation, cell fate and determination, cell differentiation, senescence, and apoptosis. Emphasis will be placed on integrating gene function and cell behavior with development. Model systems include vertebrates (e.g. frog and chick) and genetically tractable invertebrates (e.g. fruitflies and roundworms).
Prerequisites/Corequisites: Prerequisites: BIOL 2120, BIOL 2500.
When Offered: Spring term annually.
Credit Hours: 4
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BIOL 4260 - Advanced Cell Biology
This course is designed to enable students to understand how an organism functions at the cellular and molecular level, and further, how this functioning is regulated so that cells can adapt to changes in their environment. Students will learn the fundamental components of the cell (from protein to organelle), their characteristics, and how these components function in both normal and diseased cells. Students will also learn biochemical, structural, and mechanical aspects of cell functioning and regulation in normal and diseased cells. In addition, students will learn to critically read current scientific literature. By reading current literature, students will gain knowledge of the practice and presentation of science, as well as learn about new techniques and findings. This course can be used to fulfill the Culminating Experience in Biology.
Prerequisites/Corequisites: Prerequisite: BIOL 2120 and one of the following: BIOL 4620, BIOL 4760.
When Offered: Fall term annually.
Cross Listed: BIOL 6260. Students cannot receive credit for both this course and BIOL 6260.
Credit Hours: 4
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BIOL 4270 - Human Physiology
Fundamental physiological processes and their mechanism of action in human and higher mammalian organisms. Emphasis on the control and interaction of physiological systems. Introduction to the muscle, nervous, circulatory, renal, respiratory, digestive, reproductive, and hormonal systems. Limited to biology, biochemistry and biophysics, bioinformatics and molecular biology majors, and biology accelerated medical students.
Prerequisites/Corequisites: Prerequisites: BIOL 2120 or BIOL 4620, CHEM 2250, PHYS 1100. Not recommended for freshmen and sophomores.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 4310 - Microbiology
Microbiology is the study of “microscopic organisms,” including members of all the kingdoms of life. The course has two objectives: 1. Provide an overview of the diversity, genetics, and physiology of microorganisms. 2. Review current topics of investigation in Microbiology in detail. Microbes will be studied from a cellular and molecular perspective. This includes structure, nutrition, growth, control, classification and genetics. This course will provide BIOLOGY STUDENTS the necessary background in bacterial genetics, pathogenic microbiology, prokaryotic physiology, eukaryotic microbiology, molecular biology and microbial ecology.
Prerequisites/Corequisites: Biology 2120 or permission of instructor.
When Offered: Spring term annually.
Cross Listed: BIOL 6310. Students may not obtain credit for both this course and BIOL 6310.
Credit Hours: 4
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BIOL 4320 - Microbiology Lab
Microbiology Laboratory will provide hands-on experience for broad training in bacteriology and mycology with emphasis on: microscopy, bacterial growth, and biochemical assays. An investigative component will involve characterization of an unknown bacterum using the analytical tools learned. In addition to laboratory experience and good technique, the course will emphasize written communication with reports in the format of scientific papers. This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisites: BIOL 4310/6310 or permission of instructor
When Offered: Fall semester annually (beginning fall 2014).
Credit Hours: 4
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BIOL 4330 - Cancer Biology
This course is a comprehensive review of the mechanisms of cancer initiation and progression. The format is student-initiated, round-table discussions and manuscript presentations of a wide range of topics that comprise cancer biology including: tumor viruses, oncogenes and tumor suppressor genes, cell cycle regulation in cancer, growth factors and their receptors, multistep tumorigenesis, genomic instability and cancer, stromal cell-tumor cell interactions, angiogenesis, and metastatic invasion. The technique of concept mapping will be used to allow students to graphically organize their understanding of the cancer field as the course progresses. May be used to fulfill the Culminating Experience in Biology.
Prerequisites/Corequisites: Prerequisites: BIOL 2500 and BIOL 4620 or equivalent courses.
When Offered: Fall term, even-numbered years.
Cross Listed: BIOL 6330. Students may not obtain credit for both this course and BIOL 6330.
Credit Hours: 4
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BIOL 4350 - Virology
This course will provide an exploration of the essential aspects of virology. Introductory examination of viral structure, entry and replication for each of the major classes of viruses serve as a foundation. Case studies will examine virus host interactions and strategies for prevention and intervention of viral infection. Additional topics include: emerging viruses, viral detection, viral extinction, beneficial use of viruses, modified viruses as research tools.
Prerequisites/Corequisites: Prerequisite: BIOL 4620 and BIOL 4310 or permission of istructor.
When Offered: Fall term annually beginning fall 2014.
Cross Listed: BIOL 6350. A student cannot get credit for both BIOL 4350 and BIOL 6350.
Credit Hours: 4
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BIOL 4400 - Bioterrorism, Biowarfare, and Biodefense: A Clear and Present Danger
Never in the history of civilization is the use of biological weapons against humanity more likely by individuals or groups. Course material will focus on what constitutes biological weaponry. Topics include a history of biological warfare and the basic biological principles involved in the manipulation of biological agents: pathogenic microorganisms (bacteria and viruses), their toxins and their comparative lethality. Modes of environmental dissemination of agents and countermeasures that constitute biological defense will be presented. Course will include class discussion and Internet homework.
Prerequisites/Corequisites: Prerequisite: BIOL 1010 or equivalent.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 4510 - Origins of Life
To understand the origin of life is a fundamental goal of science. We discuss evidence for important prebiotic molecules in the clouds from which new planetary systems are born, and compare cosmic and terrestrial sources of such molecules on the primitive Earth. The course is multidisciplinary, covering topics in physics, astronomy, chemistry, earth sciences, and biology. Students may not obtain credit for more than one of ASTR 4510, ERTH 4510, or BIOL 4510.
Prerequisites/Corequisites: ASTR 2050 or permission of instructor.
When Offered: Spring term annually.
Cross Listed: ASTR 4510/ERTH 4510.
Credit Hours: 3
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BIOL 4540 - Sequence Analysis
This course covers the theory and practice of biological sequence analysis, including algorithms for pairwise sequence alignment, multiple sequence alignment, phylogenetic analysis, and database searching. Concepts covered include homology, sequence similarity, parsimony, mechanisms and metrics of molecular evolution, biological data bases, database search algorithms (BLAST), and statistical significance. Selected topics include hidden Markov models, bootstrap analysis and gene finding. Modern sequence analysis software will be provided. Laptop computers and programming knowledge are required. Meets jointly with BIOL 6410.
Prerequisites/Corequisites: Prerequisites: MATH 1020, BIOL 4620, CSCI 1200, or equilavent.
When Offered: Fall term annually.
Cross Listed: BIOL 6410. Both cannot be taken for credit.
Credit Hours: 4
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BIOL 4550 - Molecular Modeling
This course covers the theory and practice of the structural modeling of proteins and other biomolecules using informatics-driven and energy-based approaches. Topics include template-based comparative modeling, secondary structure prediction, tertiary structure prediction, protein classification, sidechain rotamers, docking, protein design, energy minimization, electrostatics, molecular dynamics, and molecular surfaces. Molecular modeling software will be provided. Laptop computers are required. BIOL 4550, BIOL 6420, BCBP 4550, and BCBP 6420 meet jointly; only one of these courses can be taken for credit.
Prerequisites/Corequisites: Prerequisite: MATH 1020, BIOL 4620, BIOL 4760.
When Offered: Spring term annually.
Cross Listed: BIOL 4550/6420, BCBP 4550/6420.
Credit Hours: 4
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BIOL 4620 - Molecular Biology
Nucleotide biosynthesis; structure, replication, transcription, and translation of nucleic acids; reassociation of nucleic acids; molecular cloning, sequencing, and endonuclease mapping of DNA; control of gene expression in bacteria and higher organisms.
Prerequisites/Corequisites: Prerequisites: BIOL 2120 and BIOL 2500 or permission of the instructor.
When Offered: Spring term annually.
Credit Hours: 4
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BIOL 4630 - Molecular Biology II
Students will use a variety of tools (textbooks, scientific journals, and Internet resources including molecular databases and data mining tools) to increase understanding of genes, their expression, their products, and their inter-relatedness. (Meets together with BIOL 6690. Both cannot be taken for credit.)
Prerequisites/Corequisites: Prerequisite/Corequisite: BIOL 4620 and BIOL 4760.
When Offered: Fall term annually.
Cross Listed: BIOL 6690.
Credit Hours: 4
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BIOL 4640 - Proteomics
Characterization of patterns and changes in patterns of protein expression with development, aging, and disease. Protein separation and quantification strategies; mass spectrometry and analysis of spectra; protein profiling, biomarkers, post-translational modifications; current applications; emerging technologies and applications. Individual presentations on relevant topics will be expected.
Prerequisites/Corequisites: Prerequisite: BCBP 4760 or equivalent.
When Offered: Spring term annually.
Cross Listed: BCBP 4640/6640 and BIOL 6640. Students cannot obtain credit for this course and BCBP 4640, BCBP 6640 or BIOL 6640.
Credit Hours: 4
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BIOL 4680 - Applied and Environmental Microbiology
Examination of how microorganisms interact with each other and with their environment. Microbial distribution and activities in natural systems, and their importance to ecosystem function and environmental quality. Field work and laboratory experience with both classical and modern molecular microbiological techniques including sampling and chemical and physical site characterization; enrichment techniques, fluorescence in situ hybridization, 16S rDNA amplification, sequence analysis, and probe design. Current literature regarding manipulation and regulation of microbial activities will be discussed. This course will be taught at the Darrin Fresh Water Institute at Lake George. A nominal fee will be charged for housing. The course includes extensive hands-on laboratory work as well as the writing of in-depth reports. This is a communication-intensive course.
Prerequisites/Corequisites: Prerequiste: BIOL 4310 or permission of instructor.
When Offered: Fall term annually.
Credit Hours: 4
Contact, Lecture or Lab Hours: A total of three hours of lecture/class time and three hours laboratory time is required per week.
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BIOL 4700 - Freshwater Ecology
Freshwater ecology is the quantitative examination of major biological fresh water communities. Course discussions will delineate the physical and chemical regimes under which aquatic organisms exist. Basic limnological processes are studied to define aquatic systems of differing physical characteristics. Nutrient chemistry analyses of waters of varying acidity, alkalinity, and chemical loadings are related to their trophic status. Lecture and Laboratory are taught at the Darrin Fresh Water Institute at Lake George with field activities at various locations in the Adironacks. The course includes extensive hands-on laboratory work, as well as the writing of in-depth reports. This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: BIOL 1010 or equivalent and permission of instructor.
When Offered: Fall term annually.
Cross Listed: BIOL 6700. A student cannot get credit for both this course and BIOL 6700.
Credit Hours: 4
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BIOL 4710 - Biochemistry Laboratory
Major principles of biochemistry are illustrated, as students purify and analyze specific proteins. Experience is obtained with various techniques including protein extraction from bacteria and tissues, chromatography, ultracentrifugation, spectrophotometric analysis, and electrophoresis. The course includes extensive hands-on laboratory work, as well as the writing of in-depth reports. (Students cannot obtain credit for both this course and BCBP 4710.) This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: BIOL 1010, BIOL 2120.
When Offered: Spring term annually.
Cross Listed: Cross listed with BCBP 4710.
Credit Hours: 4
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BIOL 4720 - Molecular Biology Laboratory
The techniques of gel electrophoresis, restriction enzyme mapping, PCR, and use of a molecular biology software program are applied to the study of bacterial plasmids and mammalian genes. The course includes extensive hands-on laboratory work, as well as the writing of in-depth reports. This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: BIOL 2120, BIOL 4620.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 4740 - Cell and Developmental Biology Laboratory
Students will learn a variety of modern cell and developmental biology techniques such as cell culture, genetic analysis, immunocytochemistry, fluorescence microscopy, and live cell imaging. Using these techniques, students will investigate the function of genetically manipulated proteins in cells and developing embryos. In the last third of the semester, students will develop independent experimental research plans to address questions of interest to the student. This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: BIOL 2120, BIOL 2500.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 4750 - Cell-Extracellular Matrix Interactions
Comprehensive examination of cellular interactions with the extracellular matrix (ECM), as well as analysis of the structure and function of the ECM in a variety of tissues. Topics to be covered include: ECM proteins, cell-matrix interactions, ECM signaling, mechanics of the ECM, ECM pathology, and recent advances in ECM research.
Prerequisites/Corequisites: Prerequisite: There are no formal prerequisites, but students should have a rudimentary knowledge of cell biology and protein structure (readings to provide this background can be requested from the instructor). Limited to students with junior or senior standing. Graduate students must enroll in BIOL 6750; both courses BIOL 4750 and BIOL 6750 may not be taken for credit. May be used to fulfill the Culminating Experience requirement in Biology.
When Offered: Spring term even-numbered years.
Credit Hours: 4
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BIOL 4760 - Molecular Biochemistry I
Part I of a two-semester sequence focusing on the chemistry, structure, and function of biological molecules, macromolecules, and systems. Topics covered include protein and nucleic acid structure, enzymology, mechanisms of catalysis, regulation, lipids and membranes, carbohydrates, bioenergetics, and carbohydrate metabolism.
Prerequisites/Corequisites: Prerequisites: CHEM 2250 and BIOL 1010 or BIOL 2120 or equivalent.
When Offered: Fall term annually.
Cross Listed: Cross listed as BCBP 4760 and CHEM 4760. Students cannot obtain credit for both this course and either BCBP 4760 or CHEM 4760.
Credit Hours: 4
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BIOL 4770 - Molecular Biochemistry II
The second semester of the molecular biochemistry sequence. Topics include lipids and lipid metabolism, amino acid metabolism and the coenzymes involved in this metabolism, nucleic acid synthesis and chemistry, protein synthesis and degradation, integration of metabolism, photobiology, and photosynthesis. This course is taught in studio mode. (Students cannot obtain credit for both this course and either BCBP 4770 or CHEM 4770.)
Prerequisites/Corequisites: Prerequisite: BIOL 4760 or permission of instructor.
When Offered: Spring term annually.
Credit Hours: 4
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BIOL 4850 - Principles of Ecology
A study of the fundamental principles of the ecology of plants and animals. Interrelationships between organisms and their environments are discussed as well as material and energy balances in the ecosystem. Emphasis on the biology of populations (producers, consumers, and decomposers).
Prerequisites/Corequisites: Prerequisite: BIOL 2120 or BIOL 1010.
When Offered: Spring term annually.
Credit Hours: 4
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BIOL 4860 - Evolution
Phylongeny and the patterns of evolution in the fossil record, geography of evolution, biodiversity, origin of genetic variation, genetic drift, natural selection and adaptation, genetic theory of natural selection, evolution of phenotypic traits, conflict and cooperation, speciation, fitness, coevolution, genomic evolution, evolution and development, macroevolution, evolutionary science and society. May be used to fulfill the Culminating Experience requirement in Biology. Lectures, student presentations, and peer learning.
Prerequisites/Corequisites: Prerequisite: BIOL 2500.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 4900 - Team Research
Independent research by teams under the supervision of a faculty member, including literature search, brief proposal of project design, conduct of project to completion, and writing of a formal report in the form of a scientific paper and presentation of a seminar or poster on the project. May be used to fulfill the Culminating Experience in Biology.
Prerequisites/Corequisites: Restricted to Biology majors who have completed BIOL 1010, BIOL 2120, and BIOL 2500, or equivalents and who have permission of the instructor to register.
When Offered: Fall and spring terms annually.
Credit Hours: 4
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BIOL 4940 - Readings in Biology
Selected readings in the biological literature to supplement the scientific background of undergraduate students. May be used as a biology elective with approval of Biology Department Curriculum Committee. With four credits, may be acceptable as fulfilling the Culminating Experience requirement in Biology, subject to approval of academic adviser.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Fall, spring, and summer terms annually.
Credit Hours: 1 to 4
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BIOL 4970 - Non-thesis Research
Independent study program for the purpose of developing research skills under the guidance of a faculty member. This course may be repeated once, and it can count as a biology elective. It may not meet the culminating experience requirement except by special permission of the Biology Department.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Fall, spring, and summer terms annually.
Credit Hours: 1 to 4
Contact, Lecture or Lab Hours: 3-12 contact hours.
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BIOL 4980 - Biomedical Research
Independent research in health sciences, supervised by a faculty member, for the purpose of developing research skills. Such skills include defining a research project, both as a written and oral exercise for a scientific and general audience, and gathering preliminary research data enabling both a written and oral description of the project in the form of a research proposal and an oral defense. Open to students in the accelerated physician-scientist curriculum only. This course is the Culminating Experience for students in this program. This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Spring term annually.
Credit Hours: 4
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BIOL 4990 - Senior Research Thesis
Independent research, supervised by a faculty member, culminating in a written thesis and oral presentation.This is a communication-intensive course.
Prerequisites/Corequisites: Prerequisite: Permission of instructor.
When Offered: Fall, spring, and summer terms annually.
Credit Hours: 4
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BIOL 6100 - From Neuron to Behavior
A detailed survey of important topics in the neurosciences. Some of the topics to be covered in this class are: basic mechanisms of neural signaling (neurophysiology, synaptic transmission, and molecular signaling; understanding of sensation/movement and in particular how it relates to neuroanatomy; neurodevelopment and how the mature brain can change (plasticity), and; complex brain functions and neurological disease. Students prepare analyses and make a presentation of a paper in the original literature. Since there is overlap associated with the 4100 course, both courses may not be taken for credit.
Prerequisites/Corequisites: Prerequisites: BIOL 1010, BIOL 2120 or permission of the instructor.
When Offered: Spring term annually.
Credit Hours: 4
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BIOL 6260 - Advanced Cell Biology
This course is designed to enable students to understand how an organism functions at the cellular and molecular level, and further, how this functioning is regulated so that cells can adapt to changes in their environment. Students will learn the fundamental components of the cell (from protein to organelle), their characteristics, and how these components function in both normal and diseased cells. Students will also learn biochemical, structural, and mechanical aspects of cell functioning and regulation in normal and diseased cells. In addition, students will learn to critically read current scientific literature. By reading current literature, students will gain knowledge of the practice and presentation of science, as well as learn about new techniques and findings. Students cannot receive credit for both this course and BIOL 4260.
Prerequisites/Corequisites: Prerequisites: An undergraduate “Introduction to Cell Biology” course (BIOL 2120 equivalent). Coursework in Biochemistry and Molecular Biology will be helpful, as well.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 6310 - Microbiology
Microbiology is the study of “microscopic organisms,” including members of all the kingdoms of life. The course has two objectives: 1. Provide an overview of the diversity, genetics, and physiology of microorganisms. 2. Review current topics of investigation in Microbiology in detail. Microbes will be studied from a cellular and molecular perspective. This includes structure, nutrition, growth, control, classification, and genetics. This course will provide BIOLOGY STUDENTS the necessary background in bacterial genetics, pathogenic microbiology, prokaryotic physiology, eukaryotic microbiology, molecular biology and microbial ecology.
When Offered: Spring term annually.
Cross Listed: BIOL 4310. Students may not obtain credit for both this course and BIOL 4310.
Credit Hours: 4
Contact, Lecture or Lab Hours: 6 contact hours
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BIOL 6330 - Cancer Biology
This course is a comprehensive review of the mechanisms of cancer initiation and progression. The format is student-initiated, round-table discussions and manuscript presentations of a wide range of topics that comprise cancer biology including: tumor viruses, oncogenes and tumor suppressor genes, cell cycle regulation in cancer, growth factors and their receptors, multistep tumorigenesis, genomic instability and cancer, stromal cell-tumor cell interactions, angiogenesis, and metastatic invasion. The technique of concept mapping will be used to allow students to graphically organize their understanding of the cancer field as the course progresses. May be used to fulfill the Culminating Experience in Biology.
Prerequisites/Corequisites: Prerequisites: BIOL 2500 and BIOL 4620 or equivalent courses.
When Offered: Fall term, even-numbered years.
Cross Listed: BIOL 4330. Students may not obtain credit for both this course and BIOL 4330.
Credit Hours: 4
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BIOL 6350 - Virology
This course will provide an exploration of the essential aspects of virology. Introductory examination of viral structure, entry and replication for each of the major classes of viruses serve as a foundation. Case studies will examine virus host interactions and strategies for prevention and intervention of viral infection. Additional topics include: emerging viruses, viral detection, viral extinction, beneficial use of viruses, modified viruses as research tools.
Prerequisites/Corequisites: Prerequisites: BIOL 4620 and BIOL 4310 or permission of instructor.
When Offered: Fall term annually beginning fall 2014.
Cross Listed: BIOL 4350. A student cannot get credit for both BIOL 4350 and BIOL 6350.
Credit Hours: 4
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BIOL 6410 - Sequence Analysis
This course covers the theory and practice of biological sequence analysis, including algorithms for pairwise sequence alignment, multiple sequence alignment, phylogenetic analysis, and database searching. Concepts covered include homology, sequence similarity, parsimony, mechanisms and metrics of molecular evolution, biological data bases, database search algorithms (BLAST), and statistical significance. Selected topics include hidden Markov models, bootstrap analysis, and gene finding. Modern sequence analysis software will be provided. Laptop computers are required. Knowledge of a programming language is strongly suggested. Meets jointly with BIOL 4540; both cannot be taken for credit.
Prerequisites/Corequisites: MATH 1020, BIOL 4620, CSCI 1200 or equilavent, or permission of the instructor.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 6420 - Molecular Modeling
This course covers the theory and practice of the structural modeling of proteins and other biomolecules using informatics-driven and energy-based approaches. Topics include template-based comparative modeling, secondary structure prediction, tertiary structure prediction, protein classification, sidechain rotamers, docking, protein design, energy minimization, electrostatics, molecular dynamics, and molecular surfaces. Molecular modeling software will be provided. Laptop computers are required. BIOL 4550, BIOL 6420, BCBP 4550, and BCBP 6420 meet jointly; only one of these courses can be taken for credit.
Prerequisites/Corequisites: MATH 1020, BIOL 4620, BIOL 4760.
When Offered: Spring term annually.
Cross Listed: BIOL 4550/6420, BCBP 4550/6420.
Credit Hours: 4
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BIOL 6510 - Biology Core Course 1
An intensive course designed to provide instruction and stimulate discussion on important topics in biological research. It is loosely divided into 4 modules: 1) ethics, writing, and basic computational biology tools; 2) structural and computational biology; 3) protein and carbohydrate structure and function; 4) microbiology, ecology, and evolution. Students will gain a fundamental understanding of major topics in biology through formal didactic instruction and selected readings from the primary literature.
Prerequisites/Corequisites: Completed bachelor’s degree or permission of instructor.
When Offered: Fall term annually.
Credit Hours: 4
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BIOL 6520 - Biology Core Course II
An intensive course designed to provide instruction and stimulate discussion on important topics in biological research. It is loosely divided into three modules: 1) molecular biology and genetics; 2) cell biology; and 3) entrepreneurship/leadership. Students will gain a fundamental understanding of major topics in biology through formal didactic instruction and selected readings from the primary literature.
Prerequisites/Corequisites: Prerequisite: This is a continuation of the fall course BIOL 6510. Completed bachelor’s degree or permission of instructor.
When Offered: Spring term annually.
Credit Hours: 4
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BIOL 6550 - Ethical Issues in Biotechnology
This course reviews the principles of ethical behavior and responsible conduct of research and discusses specific areas of biotechnology research, medical research and societal issues in the context of these principles. Representative topics include genetic engineering, stem cell research, assisted reproduction, human subjects, animal research and nanotechnology. Active student participation is expected.
Prerequisites/Corequisites: Undergraduate registration only with permission of instructor.
When Offered: Fall term annually.
Cross Listed: BCBP 6550 and BMED 6700. Students may not receive credit for both BIOL 6550 and BCBP 6550 or BMED 6700.
Credit Hours: 3
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BIOL 6640 - Proteomics
Characterization of patterns and changes in patterns of protein expression with development, aging, and disease. Protein separation and quantification strategies; mass spectrometry and analysis of spectra; protein profiling, biomarkers, post-translational modifications; current applications; emerging technologies and applications. Individual presentations on relevant topics will be expected.
Prerequisites/Corequisites: Prerequisite: BCBP 4760 or equivalent.
When Offered: Spring term annually.
Cross Listed: BIOL 4640, BCBP 4640, BCBP 6640. Students cannot obtain credit for this course and BCBP 4640, BIOL 4640, or BCBP 6640.
Credit Hours: 3
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